Hotel Los Amantes

Hotel Los Amantes is named after a well-known Oaxacan mezcal brand and leans into the association — the hotel and its namesake spirit share the same idea of Oaxacan craft done with care. The rooms are curated individually with local art rather than run off a single template, so the hotel reads more like a small gallery with beds in it than a standard boutique stay.

It sits in Centro within easy walking distance of the Zócalo and Santo Domingo, close enough to skip taxis for most of a day out. The style is more design-forward than luxury-polished, which suits people who want character over uniformity.

Book a room with a courtyard or rooftop view if you can — that's where the building's age and restoration show best.